The Couple Next Door came to an end tonight (23rd July), with Jacob (Sam Palladio) being exposed as the culprit behind the string of mysterious deaths at the hospital - crimes he tried to frame Mia (Aggy K. Adams) for.

Jacob's wife, Charlotte, uncovered the truth and in a bid to cover up his crimes, he poisoned her coffee and made it look like she'd taken her own life.

It's a twist we never saw coming, with so many eyes on Mia, but Sam Palladio tells Cosmopolitan UK that there was a very subtle clue in episode two - one he he had to go back and watch himself.

"I think the first thing that really triggers everything is that initial mistake - it's very subtly done," Palladio explained, referencing the moment when Jacob entered a patient's room and reached for a syringe, but became too distracted by Mia - who was thanking him for defending her earlier that day - to administer the medicine.

the couple next door season 2 jacob and charlottepinterest
Channel 4

He continued: "I think it's episode two or three. Maybe it's episode two where Mia is sort of thanking him in the suite for for saying what he said to that evil patient, Mr. Green, who was a perve and there's a subtle slip up. We didn't want to telegraph that the medicine didn't go in and we need to re-inject, but that's what he does."

In the episode we see Jacob holding the medicine in his hand as Mia thanks him, saying: "By the way can I just say, I didn't get to thank you for being so kind earlier."

He replies: "No worries, I didn't want you to think I was trying to rescue you. I know you can take care of yourself."

She then says: "Oh God no, I didn't think that. I'll let myself be rescued, but I must say this time it felt really nice. It felt good to feel protected in a way."

"Oh any time," he smiles.

the couple next door's mia being groped by the patient in episode 2pinterest
Toon Aerts

The scene then cuts to Charlotte at the care home with her dad Henry and Alan, meaning we never actually get to see Jacob inject the medicine.

The next time we see him, the patient is flatlining and he's scrambling to save him.

Palladio continued: "He tries to cover his track when that guy starts flatlining. And so when you go back and you see, that's the moment where he's subtly injecting something to cover his tracks, and he shouldn't be. And so I think it's intriguingly done."

While Jacob is trying to save the patient, Mia stands in the corner, shell-shocked, and once the patient is pronounced dead, she says: "He wasn’t a very nice man," immediately raising suspicion.

"I think that there was such a great job of making Mia such an intriguing dark [character] with her history. So you go, 'Well of course, it's her!'" Palladio said.

The Couple Next Door seasons one and two are available to stream on Channel4.com